We are excited to announce a new chapter authored by our researchers, Tuba Okur and Onur Serçinoğlu, published in the Encyclopedia of Bioinformatics and Computational Biology (Second Edition).
This chapter provides an overview of computational protein engineering methods, with a focus on modifying enzyme sequences and structures for enhanced catalytic activity, stability, specificity, and reaction yield. Examples of successful protein engineering applications are provided throughout the chapter.
The chapter highlights the transformative role of computational tools in overcoming traditional limitations in protein engineering. It discusses how computational approaches have revolutionized the field by enabling precise modifications to protein structures and functions, leading to improved therapeutic applications and industrial processes.
Additionally, the chapter discusses future prospects for refining predictive models to advance the protein engineering field, providing valuable insights for researchers working on next-generation protein design and optimization strategies.
For more details, you can read the full chapter here.